Latest Publication of L.-S. Kan, ¥Ì¾|¥Í

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  1. Polyproline II helix is a key structural motif of the elastic PEVK segment of titin, K. Ma, Lou-sing Kan, K. Wang, Biochemistry, 40, 3427-3438 (2001)

  2. Photochemical cleavage of single- and double-stranded oligonucleotides by 3-(p-tolylamino)-1,5-azulenequinone, F.-Y. Tsai, S.-B. Lin, S.-C. Tsay, W.-C. Lin, C.-L. Hsieh, S. H. Chuang, Lou-sing Kan, and J. R. Hwu, Tetrahedron Let., 42, 5733-5735(2001).

  3. Interaction between 3-(p-Tolylamino)-1,5-Azulenequinone and the deoxyguanosine residue in various oligonucleotides upon photolysis, J. R. Hwu, F.-Y. Tsai, S.-C. Tsay, S. H. Chuang, T.-R. Su, S.-B. Lin, W.-C. Chen, C.-L. Hsieh, and Lou-sing Kan, Photochem. Photobiol., 74, 686-693 (2001)

  4. Effects of polyamines on the thermal stability and formation kinetics of DNA duplexes with abnormal sequence, M.-H. Hou, S.-B. Lin, J.-M. Yuann, W.-C. Lin, A. H.-J. Wang, and Lou-sing Kan, Nucleic Acids Res., 29, 5121-5128 (2001).

  5. Formation of DNA triple helix containing N4-(6-aminopyridin-2-yl)-2¡¦-deoxycytidine, T.-M. Chin, M.-H Tseng, K.-Y. Chung, F.-S. Hung, S.-B. Lin, and Lou-sing Kan, J. Biomol. Str. Dyn., 19, 543-553 (2001).

  6. Proton NMR Studies of 5'-d-(TC)3(CT)3(AG)3 ¡V A Paperclip Triplex: The Structural Relevance of Turns, Pasternack, L., Lin, S.-B., Chin, T.-M., Lin, W.-C., Huang, D.-H., and Kan, L.-S. Biophysical J., 82, 3170-3180 (2002).

  7. Protein Folding by A Quasi-static-like Process: A First-order State Transition, Chang, C.-C., Su, Y.-C., Cheng, M.-S., and Kan, L.-S. Phys. Rev., E., 66, 021903(1-8), (2002). (Also being selected for Virtual Journal of Biological Physics Research, 4, issue 4 (August 15, 2002))

  8. Triterpene extract from Ganoderma lucidum inhibits growth of hepatoma Huh7 cells: involvement of oxidative stress induction, Lin, S.-B., Li, C.-H., Chen, Y.-R., Kan, L.-S, Lee, S.-S. In: Lin Z.-B. (Ed.), ¡§Ganoderma: Genetics, Chemistry, Pharmacology and Therapeutics¡¨. Beijing Medical University Press, Beijing, pp 176-182 (2002).

  9. Proton NMR Study on Two Structures of 3'-O-(Acetylimino)3'-de(phosphinico)-thymidylyl-(3,5')-deoxythymidine in Aqueous Solution, Tseng, Y.-Y., Yang, T.-F., and Kan, L.-S. Tetrahedron, 59, 1981-1988, (2003).

  10. Triterpene-enriched extracts from Ganoderma lucidum inhibit growth of hepatoma cells via suppressing protein kinase C, activating mitogen-activated protein kinases and G2-phase cell cycle arrest, Lin, S.-B., Li, C.-H., Lee, S.-S., Kan, L.-S. Life Sci, 72, 2381-2390, (2003).

  11. Reversible Folding of Cysteine-Rich Metallothionein by an Over-Critical Reaction Path, Yi-Liang Liu, Hui-Ting Lee, Chia-Ching Chang, and Lou-sing Kan, Biochem. Biophys. Res. Commun. 306, 59-63 (2003).

  12. Production and characterization of bioactive recombinant resistin in E. coli., Juan, C.-C., Kan, L.-S., Huang, C.-C., Chen, S.-S., and Au, L.-C., Biotechnology, 103, 103-107 (2003).

  13. A First-Order-Like State Transition for Recombinant Protein Folding, C.-C. Chang, M.-S. Cheng, Y.-C. Su, and Lou-sing Kan, J. Biomol. Str. Dyn., 21, 247-255 (2003).

  14. Refolding of Lysozyme by Quasi-static and Direct Dilution Reaction Paths: A First-Order-Like State Transition, Chia-Ching Chang, Xu-Cheng Yeh, Hui-Ting Lee, Po-Yen Lin, and Lou-Sing Kan, (2004) Phys. Rev., E., 70, 011904 (1-8) (2004). (Also being selected for Virtual Journal of Biological Physics Research, 8, issue 2 (July 15, 2004))

  15. Protein folding stabilizing time measurement: a direct folding process and three-dimensional random walk simulation, Chia-Ching Chang, Po-Yen Lin, Xu-Cheng Yeh, Kuang-Hau Deng, Yen-Peng Ho and Lou-Sing Kan, Biochem. Biophys. Res. Commun. 328, 845-50 (2005).

  16. Studies on the extension of sequence-independence and the enhancement of DNA triplex formation, Ming-Tsi Wei, Axel Walter, Anna Gabrielian, Holger Schutz, Eckhard Birch-Hirschfeld, Shwu-Bin Lin, Wei-Chen Lin, Hartmut Fritzsche, and Lou-sing Kan, J. Chin. Chem. Soc., 52, 375-381 (2005).

  17. Ganoderic acid X, a lanostanoid triterpene, inhibits topoisomerases and induces apoptosis of cancer cells, Chyi-Hann Li, Pei-Yu Chen, Ue-Min Chang, Lou-Sing Kan, Woei-Horng Fang, Keh-Sung Tsai, Shwu-Bin Lin, Life Sci., 77, 252-265 (2005).