Alternative Splicing as a Switch to Accelerate or Decelerate Evolution of Protein Subsequences
Feng-Chi Chen1, Yun-Huei Tzeng2, Sheng-Shun Wang3, and Trees-Juen Chuang2*
1Division of Biostatistics and Bioinformatics, National Health Research Institute, 35 Keyan Road, Zhunan Town, Miaoli County 350, Taiwan,
2Genomics Research Center, Academia Sinica, 128 Academia Road Sec. 2, Nankang, Taipei 11529, Taiwan
3Institute of Information Science, Academia Sinica, 128 Academia Road Sec. 2, Nankang, Taipei 11529, Taiwan
* To whom correspondence should be addressed.
Email: trees@gate.sinica.edu.tw
Contact: Dr.Trees-Juen Chuang
Genomics Research Center, Academia Sinica, Taipei 11529, Taiwan
The retrieved human-mouse orthologous exon pairs:
| Datasets used in the study | Descriptions |
| Dataset 1 | Sequences of the retrieved human-mouse orthologous exon pairs, including conserved ASEs, ASE-CSE, CSE-ASE, and conserved CSEs. |
| Dataset 2 | Sequences of the retrieved human-mouse orthologous exon pairs, including human and mouse simple/complex ASEs of Group 1 in Table 2. |
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Acknowledgements
This work is supported by the Genomics Research Center (GRC), Academia Sinica, Taiwan and the National Health Research Institutes (NHRI), Taiwan, under contract NHRI-EX95-9408PC. We thank EBI-ASD Web interface for freely downloaded data and Chuang-Jong Chen for assistance in data collection.