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Human, chimpanzee, and macaque gene copies used in the study
Gene family size conservation is an important indicator of evolutionary
rates and gene essentiality
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Feng-Chi Chen1, Chueng-Jong Chen2, Wen-Hsiung Li3,4*, and Trees-Juen Chuang2*
1Division of Biostatistics and Bioinformatics, Institute of Population Health Sciences, National Health Research Institutes, Miaoli County 350, Taipei, Taiwan.
2Genomics Research Center and 2Institute of Information Science, Academia Sinica, Taipei 11529, Taiwan.
3Department of Evolution and Ecology, University of Chicago, 1101 East 57th Street, Chicago, IL 60637, USA
4Biodiversity Research Center and Genomics Research Center, Academia Sinica, Taipei 11529, Taiwan
*Ccorresponding authors: Li, W.-H. (wli@uchicago.edu) and Chuang, T.-J. (trees@gate.sinica.edu.tw).
Contact: Dr. Trees-Juen Chuang
Genomics Research Center, Academia Sinica, Taipei 11529, Taiwan
Acknowledgments: This work is supported by the Genomics Research Center, Academia Sinica, Taiwan; the National Health Research Institutes (NHRI), Taiwan (under contract NHRI-EX98-9408PC); National Science Council, Taiwan (under contract NSC 96-2628-B-001-005-MY3; to TJC); and NHRI intramural funding (to FCC). We especially thank Prof. Ben-Yang Liao for providing the data of human and mouse essential genes. We also thank the system manager of the UCSC genome browser for supplying Chimpanzee and Macaque self chained alignments.
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Last update: September 3, 2009