|
|
|
|
List of Publications |
|
98) |
Chem Asian J., 8(12), 3191-3199 (2013) |
|
B. Ghosh, Y.-H. Lai, Y.-Y. Shih, T. K. Pradhan, C.-H. Lin*, K.-K. T. Mong |
|
“Total Synthesis of a Glycoglycerolipid from Meiothermus taiwanensis through a One-Pot Glycosylation Reaction and Exploration of its Immunological Properties” |
|
97) |
Proc. Natl. Acad. Sci. USA, 110(34), 13809-13814 (2013) |
|
S.-F. Liao, C.-H. Liang, M.-Y. Ho, T.-L. Hsu, T.-I. Tsai, Y. S.-Y. Hsieh, S.-T. Li, Y.-Y. Cheng, S.-M. Tsao, T.-Y. Lin, Z.-Y. Lin, W.-B. Yang, C.-T. Ren, K.-I. Lin, C.-H. Lin, H.-Y. Hsu, C.-Y. Wu, C.-H. Wong* |
|
“Immunization of fucose-containing polysaccharides from Reishi mushroom induces antibodies to tumor-associated Globo H-series epitopes” |
|
96) |
Proc. Natl. Acad. Sci. USA, 110(27), 10928-10933 (2013) |
|
H.-W. Huang, C.-H. Chen, C.-H. Lin, C.-H. Wong, K.-I. Lin* |
|
“B-cell maturation antigen is modified by a single N-glycan chain that modulates ligand binding and surface retention"” |
|
95) |
Chem Soc Rev., 42(10), 4459-4475 (2013) |
|
Z. Tu, Y.-N. Lin, C.-H. Lin* |
|
“Development of fucosyltransferase and fucosidase inhibitors” |
|
94) |
Tetrahedron, 69(19), 3991-3999 (2013) |
|
Z.-P. Lin, F.-F. Wong, Y.-B. Chen, C.-H. Lin, M.-T. Hsieh, J.-C. Lien, Y.-H. Chou, H.-C. Lin |
|
“Regioselective and Reductive Cleavage of Allyl Ethers by NaBH4-HOAc” |
|
93) |
Chem Asian J., 8(7), 1536-1550 (2013) |
|
Z. Tu, H.-W. Hsieh, C.-M. Tsai, C.-W. Hsu, S.-G. Wang, K.-J. Wu, K.-I. Lin*, C.-H. Lin* |
|
“Synthesis and characterization of sulfated Gal-β-1, 3/1,4 -GlcNAc disaccharides through consecutive protection /glycosylation steps” |
|
92) |
Med Chem Comm, 4(5), 783-791 (2013) |
|
J.-T. Wang, T.-C. Lin, Y.-H. Chen, C.-H. Lin* and J.-M. Fang* |
|
“Polyhydroxylated pyrrolidine and 2-oxapyrrolizidine as glycosidase inhibitors” |
|
91) |
ChemBioChem, 14(7), 813-817 (2013) |
|
J. C.-Y. Lin, C.-C. Chou, S. Gao, S.-C. Wu, K.-H. Khoo, C.-H. Lin* |
|
“An in vivo tagging method reveals That Ras undergoes sustained activation upon transglutaminase-mediated protein serotonylation” |
|
90) |
Chem Commun, 49(39), 4265-4267 (2013) |
|
S.-M. Chang, Z. Tu, H.-M. Jan, J.-F. Pan, C.-H. Lin* |
|
“Rapid synthesis of oligomannosides with orthogonally protected monosaccharides” |
|
89) |
Tetrahedron, 69(11), 2494-2500 (2013) |
|
Z.-P. Lin, F.-F. Wong, Y.-B. Chen, Y.-C. Lin, M. Kimura, K. Kaneko, H. Takayama, J.-B. Wu, C.-H. Lin*, H.-C. Lin*, |
|
“Synthesis of α-2-Deoxy-Ulosides by Michael Addition of Hex-1-en-3-ones” |
|
88) |
Chem Commun, 48(72), 9083-9085 (2012) |
|
R. A. Davis, C.-H. Lin, J. Gervay-Hague |
|
“Chemoenzymatic synthesis of cholesteryl-6-O-tetradecanoyl-α-D-glucopyranoside: A product of host cholesterol efflux promoted by Helicobacter pylori” |
|
87) |
Angew Chem Int Ed Engl., 51(24), 5871-5875 (2012) |
|
Chiang BY, Chou CC, Hsieh FT, Gao S, Lin JC, Lin SH, Chen TC, Khoo KH, Lin CH. |
|
“In Vivo Tagging and Characterization of S-Glutathionylated Proteins by a Chemoenzymatic Method” |
|
86) |
Future Virology, 7(6), 621-633 (2012) |
|
Y.-F. Wang, W.-I. Liao, Y.-D. Kuo, S.-Y. Guu, H.-C. Wang, C.-H. Lin, I.-J. Su, C.-F. Chang |
|
“Receptor binding surveillance of influenza clinical isolates” |
|
85) |
Adv. Synth. Catal, 354(9), 1750-1758 (2012) |
|
Y.-N. Lin, D. B. Stein, S.-W. Lin, S.-M. Chang, T.-C. Lin, Y.-R. Chuang, J. Gervay-Hague, H. Narimatsu, C.-H. Lin |
|
“Chemoenzymatic Synthesis of GDP-l-Fucose Derivatives as Potent and Selective α-1,3-Fucosyltransferase Inhibitors” |
|
84) |
Apoptosis, 17(2), 154-163 (2012) |
|
P.-Y. Yang, W.-X. Chen, F.-Y. Chang, H.-W. Chen, C.-H. Lin, Y.-C. Hsu, J. Hsieh Wu |
|
“HepG2 cells infected with Klebsiella pneumonia show DNA laddering at apoptotic and necrotic stages” |
|
83) |
Carbohydrate Research, 346(2), 183-190 (2011) |
|
Shih TL, Liang MT, Wu KD, C.-H. Lin |
|
“Synthesis of polyhydroxy 7- and N-alkyl-azepanes as potent glycosidase inhibitors” |
|
82) |
Bioresource Technol, 102(21), 10136-10138 (2011) |
|
C.-M. Chau, K.-J Liu, C.-H. Lin |
|
“Enzymatic synthesis of sialic acid derivatives by immobilized lipase from Candida antarctica” |
|
81) |
Chembiochem, 12(15), 2306-2309 (2011) |
|
C.-M. Chong, S. Gao, B.-Y. Chiang, W.-H. Hsu, T.-C. Lin, T.-C. Chen, C.-H. Lin* |
|
“An Acyloxymethyl Ketone-Based Probe to Monitor the Activity of Glutathionylspermidine Amidase in Escherichia coli” |
|
80) |
J Immunol, 187(4), 1643-1652 (2011) |
|
C.-M. Tsai, C.-H. Guan, H.-W. Hsieh, T.-L. Hsu, K.-J. Wu, Z.-J. Tu, C.-H. Lin*, K.-I. Lin* |
|
“Galectin-1 and galectin-8 have redundant roles in promoting plasma cell formation” |
|
79) |
Tetrahedron, 67 (34), 6362-6368 (2011) |
|
H.-C. Lin, J.-F. Pan, Y.-B. Chen, Z.-P. Lin, C.-H. Lin* |
|
“"Stereoselective glycosylation of endo-glycals by microwave- and AlCl3-assisted catalysis” |
|
78) |
J Struct Biol, 175(3), 300-310 (2011) |
|
Y.-Y. Chen, T.-P. Ko, C.-H. Lin, W.-H. Chen, A. H.-J. Wang* |
|
“Conformational change upon product binding to Klebsiella pneumoniae UDP-glucose dehydrogenase: A possible inhibition mechanism for the key enzyme in polymyxin resistance” |
|
77) |
Future Med Chem, 3(3), 283-296 (2011) |
|
W.-I. Liao, Y.-F. Wang, Y.-D. Kuo, Y.-D., C.-H. Lin, T.-C. Chang I.-J. Su, J.-R. Wang, C.-F. Chang* |
|
“Profiling of influenza viruses by high-throughput carbohydrate membrane array” |
|
76) |
Glycobiology, 21(7), 895-902 (2011) |
|
C.-F. Chang, J.-F. Pan, C.-N. Lin, I.-L. Wu, C.-H. Wong, C.-H. Lin* |
|
“Rapid characterization of sugar-binding specificity by in-solution proximity binding with photosensitizers” |
|
75) |
J Biol Chem, 286(16), 14057-14064 (2011) |
|
C.-Y. Chou, T.-P. Ko, K.-J. Wu, K.-F. Huang, C.-H. Lin, C.-H. Wong, A. H.-J. Wang* |
|
“Modulation of substrate specificities of D-sialic acid aldolase through single mutation of Val251” |
|
74) |
Protein Sci, 20(3), 557-566 (2011) |
|
P.-H. Pai, H.-J. Wu, C.-H. Lin*, A. H.-J. Wang* |
|
“Structure and mechanism of E. coli glutathionylspermidine amidase belonging to the family of cysteine, histidine-dependent amidohydrolase/peptodase” |
|
73) |
Exp Biol Med, 236(2), 219-26 (2011) |
|
P.-C. Pan, H.-W. Chen, P.-K. Wu, Y.-Y. Wu, C.-H. Lin, J.-H. Wu* |
|
“Mutation in fucose synthesis gene of Klebsiella pneumonia affects capsule composition and virulence in mice” |
|
72) |
Tetrahedron, 66(27-28), 5229-5234 (2010) |
|
Hui-Chang Lin, Yen-Bo Chen, Zi-Ping Lin, Fung Fuh Wong, Chun-Hung Lin and Shao-Kai Lin |
|
“Synthesis of 1,7-dioxaspiro[5.5]undecanes and 1-oxa-7-thiaspiro[5.5]undecanes from exo-glycal” |
|
71) |
ChemBioChem, 11(14), 1971-1974 (2010) |
|
A. L. van Bueren, S. D. Popat, C.-H. Lin, G. J. Davies |
|
“Structural and Thermodynamic Analysis of α-L-Fucosidase Inhibitors” |
|
70) |
J. Biol. Chem, 285(33), 25345-25353 (2010) |
|
B.-Y. Chiang, T.-C. Chen, C.-H. Pai, C.-C. Chou, H.-H. Chen, T.-P. Ko, W.-H. Hsu, C.-Y. Chang, W.-F. Wu, A. H.-J. Wang, C.-H. Lin |
|
“Protein S-Thiolation by Glutathionylspermidine (Gsp): The role of E. coli Gsp synthetase/amidase in redox regulation” |
|
69) |
ACS Chem. Biol. 5(5), 489-497 (2010) |
|
C.-W. Ho, S. D. Popat, T.-W. Liu, K.-C. Tsai, M.-J. Ho, W.-H. Chen, A.-S. Yang and C.-H. Lin |
|
“Development of GlcNAc-Inspired Iminocyclitiols as Potent and Selective N-Acetyl-β-Hexosaminidase Inhibitors” |
|
68) |
Angew. Chem. Int. Ed. 49(2), 337-340 (2010) |
|
H.-J. Wu, C.-W. Ho, T.-P. Ko, S.s. Popat, C.-H Lin and A.H.-J.Wang |
|
“Structural Basis of α-Fucosidase Inhibition by Iminocyclitols with Ki Values in the Micro- to Picomolar Range” |
|
67) |
Journal of Structural Biology 169(1), 25-35 (2010) |
|
Y.-Y. Chen, T. P. Ko, W.-H. Chen, L.-P. Lo, C.-H. Lin, A. H.-J. Wang |
|
“Conformational changes associated with cofactor/substrate binding of 6-phosphogluconate dehydrogenase from Escherichia coli and Klebsiella pneumoniae: Implications for enzyme mechanism” |
|
66) |
Tetrahedr.Lett. 50, 7327-7329 (2009) |
|
H.-C. Lin, H.-H. Wu, Z.-P. Lin, C.-Y. Lin, C.-H. Lin, K.-L. Chen, F. F. Wong, |
|
“Microwave-assisted stereoselective α-2-deoxyglycosylation of hex-1-en-3-uloses” |
|
65) |
Proc. Natl. Acad. Sci. USA 106, 14581-14586 (2009) |
|
T.-W. Liu, C.-W. Ho, H.-H. Huang, S.-M. Chang, S. D. Popat, Y.-T. Wang, M.-S. Wu, Y.-J. Chen and C.-H. Lin |
|
“Role for α-L-Fucosidase in the Control of Helicobacter pylori–infected Gastric Cancer Cells” |
|
64) |
Biochemistry, 48, 110-120 (2009) |
|
S.-W. Liu, C.-S. Chen, S.-S. Chang, K.-K. Mong, C.-H. Lin, C.-W. Chang, C.-Y. Tang, Y.-K. Li |
|
“Identification of essential residues of human alpha-L-fucosidase and tests of its mechanism” |
|
63) |
J. Biol. Chem. 283, 12343-12353 (2008) |
|
H.-J. Hsu, K.-C. Tsai, Y.-K. Sun, H.-J. Chang, Y.-J. Huang, H.-M. Yu, C.-H. Lin, S.-S. Mao, A.-S. Yang |
|
“Factor-XaActive Site Substrate Specificity with Substrate Phage Display and Computational Molecular Modeling” |
|
62) |
Blood 112, 3661-3670 (2008) |
|
C.-S. Shi, G-Y. Shi, S.-M. Hsiao, Y.-C. Kao, K.-L. Kuo, C.-Y. Ma, C.-H. Kuo, B.-I. Chang, C.-F. Chang, C.-H. Lin, C.-H. Wong, H.-L. Wu |
|
“Lectin-like domain of thrombomodulin binds to its specific ligand Lewis y antigen and neutralizes lipopolysaccahride-induced inflammatory response.” |
|
61) |
Infection and Immunity 76, 1170-1178, (2008) |
|
C. Y. Yeh, C. N. Lin, C. F. Chang, C. H. Lin, H. T. Lien, J. Y. Chen and J. S. Chia. |
|
“C-terminal repeats of Clostridium difficile toxin A induce production of chemokine and adhesion molecules in endothelial cells and promote migration of leukocytes.” |
|
60) |
Adv. Synth. Catal. 350, 2313-2321, (2008) |
|
D. B. Stein, Y.N. Lin, C.H. Lin. |
|
“Characterization of Helicobacter pylori α1,2-Fucosyltransferase for Enzymatic Syntehsis of Tumor-Associated Antigens.” |
|
59) |
Bioorg. Med. Chem. 16, 4652-4660, (2008) |
|
Y.M. Shao, W.B. Yang, T.H. Kuo, K.C. Tsai, C.H. Lin, A.S. Yang, P.H. Liang, C.H. Wong |
|
“Design, synthesis, and evaluation of trifluoromethyl ketones as inhibitors of SARS-CoV 3CL protease.” |
|
58) |
ChemBioChem 8, 1654-1657 (2007) |
|
Y.-M. Shao, W.-B. Yang, H.-P. Peng, M.-F. Hsu, K.-C. Tsai, T.-H. Kuo, A.H.-J. Wnag, P.-H. Liang, C.-H. Lin, A.-S. Yang, C.-H. Wong |
|
“Structure-based design and synthesis of highly potent SARS-CoV 3CL protease inhibitors.” |
|
57) |
J. Org. Chem. 72, 4258-4261, (2007) |
|
T.-L. Shih, R.-Y. Yang, S.-T. Li, S.-H. Wang, C.-F. Chiang, C.-H. Lin |
|
“Expeditious Synthesis of Tri- and Tetrahydroxyazepanes from D-(-)-Quinic Acid as Potent Glycosidase Inhibitors.” |
|
56) |
J. Biol. Chem. 282, 9973-9982, (2007) |
|
H.-Y. Sun, T.-P. Ko, S.-W. Lin, J.-L. Liu, A. H.-J. Wang and C.-H. Lin |
|
“Structure and Mechanism of Helicobacter pylori Fucosyltransferase: A Basis for LPS Variation and Inhibitor Design” |
|
55) |
EMBO J. 25, 5970-5982, (2006) |
|
C.-H. Pai, B.-Y. Chiang, T.-P. Ko, C.-C Chou, C.-M. Chong, F.-J. Yen, S. Chen, J. K. Coward, A. H.-J. Wang and C.-H. Lin |
|
“Dual binding sites for translocation catalysis by Escherichia coli glutathionylspermidine synthetase” |
|
54) |
J. Virol. Methods 137, 82-87, (2006) |
|
Y.-S. E. Cheng, K.-H. Lo, H.-H. Hsu, Yi-Ming Shao, W.-B.Yang, C.-H. Lin, C.-H. Wong |
|
“Screening for HIV protease inhibitors by protection against activity-mediated cytotoxicity in E. coli” |
|
53) |
J. Biol. Chem. 281, 38653-38662, (2006) |
|
H.-J. Lee, Y.-S. Chen, C.-Y. Chou, C-H. Chien, C.-H. Lin, G. G. Chang, X. Chen |
|
“Investigation of the dimer interface and substrate specificity of prolyl dipeptiase DPP8” |
|
52) |
Biochemistry. 45, 8108-8116, (2006) |
|
S.-W. Lin, T.-M. Yuan, J.-R. Li and C.-H. Lin |
|
“Carboxy1 Terminus of Helicobacter pylori α1,3-Fucosyltransferase Determines the
Structure and Stability” |
|
51) |
Biochemistry. 45, 7006-7012, (2006) |
|
C.-H. Chien, C.-H. Tsai, , C.-H. Lin, C.-Y. Chou, X. Chen |
|
“Identification of hydrophobic residues critical for DPP-IV dimerization” |
|
50) |
Carbohydr. Res. 341, 1428-1437, (2006) |
|
S.-J. Hsu, H.-C. Lin, C.-H. Lin |
|
“Inter- and Intramolecular Glycosylation of exo-Glycals Promoted by Metallic Lewis Acid” |
|
49) |
Biochemistry. 45, 5695-5702, (2006) |
|
C.-W. Ho, C.-F. Chang, Y.-N. Lin, H.-T. Lee, Y.-T. Wu, C.-Y. Wu, S.-W. Liu, Y.-K. Li, C.-H. Lin |
|
“Discovery of Different Types of Inhibition between the Human and Thermotoga maritime a-Fucosidases by Fuconojirimycin-Based Derivatives” |
|
48) |
Cancer Research. 66, 2937-45, (2006) |
|
J. Yin, A. Hashimoto, M. Izawa, K. Miyazaki, G.-Y. Chen, H. Takematsu, Y. Kozutsumi, A. Suzuki, K. Furuhata, F.-L. Cheng, C.-H. Lin, C. Sato, K. Kitajima and R. Kannagi |
|
“Hypoxic culture induces expression of sialin, a sialic acid transporter, and cancer-associated gangliosides containing non-human sialic acid on human cancer cells” |
|
47) |
J. Biol. Chem. 281, 7605-13, (2006) |
|
S.-C. Chen, Y.-C. Chang, C.-H. Lin, C.-H. Lin, and S.-H. Liaw |
|
“Crystal Structure of Bifunctional Deaminase and Reductase from Bacillus Substilus Involved in Riboflavin Biosynthsis” |
|
46) |
J. Biomed. Sci. 13, 59-72, (2006) |
|
C.-K. Chang, S.-C. Sue, T.-H. Yu, C.-M. Hsieh, C.-K. Tsai, Y.-C. Chiang, S.-J Lee, H.-H. Hsiao, W.-J. Wu, W.-L. Chang, C.-H. Lin and T.-H. Huang |
|
“Modular Organization of SARS Coronavirus Nucleocapsid Protein” |
|
45) |
J. Med. Chem. 48, 4469-4473, (2005) |
|
J.-J. Shie, J.-M. Fang, C.-J. Kuo, T.-H. Kuo, P.-H. Liang, H.-J. Huang, W.-B. Yang, C.-H. Lin, J.-L. Chen, Y.-T. Wu, and C.-H. Wong |
|
“Discovery of Potent Anilide Inhibitors against the Severe Acute Respiratory Syndrome 3CL Protease” |
|
44) |
Curr. Topics Med. Chem. 5, 1431-1457, (2005) |
|
C.-H. Lin, H.-C. Lin, W.-B. Yang |
|
“exo-Glycals: Some General Aspects and Synthetic Applications for Biochemical Use” |
|
43) |
Tetrahedron Lett. 46, 5071-5076, (2005) |
|
H.-C. Lin, W.-P. Du, C.-C. Chang, C.-H. Lin |
|
“Different Reaction Routes Found in Acid-Catalyzed Glycosylation of endo- and exo-Glycals: Competition between Ferrier Rearrangement and Protonation” |
|
42) |
Adv. Synth. Catal 347, 967-972, (2005) |
|
C.-F. Teo, T.-S. Hwang, P.-H. Chen, C.-H. Hung, H.-S. Gao, L.-S. Chang, C.-H. Lin |
|
“Synthesis of Sialyl TN Glycopeptides― Enzymatic Sialylation by α2,6-Sialyltransferase from Photobacterium damsela” |
|
41) |
Tetrahedron 61, 1855-1862, (2005) |
|
Fan, G.-T.; Pan, Y.-s.; Lu, K.-C.; Cheng, Y.-P.; Wong, C.-H.; Lin, W.-C.; Lin, C.-H.; Fang, J.-M.; Lin, C.-C. |
|
“Synthesis of a-Galactosyl Ceramide and the Related Glycolipids for Evaluation of Their Activities on Mouse Splenocytes” |
|
40) |
Tetrahedron: Asymmetry. 16, 297-301, (2005) |
|
H.-C. Lin, C.-C. Chang, J.-Y. Chen, C.-H. Lin |
|
“Streoselective Glycosylation of exo-Glycals by Microwave-assisted Ferrier Rearrangement“ |
|
39) |
J. Am. Soc. Mass Spectrom. 16, 324-332, (2005) |
|
H.-H. Huang, H.-K. Liao, Y.-J. Chen, T.-S. Hwang, Yi-Han Lin, C.-H. Lin |
|
“Structural Characterization of Sialic Acid Synthase by Electrospray Mass Spectrometry: A Tetrameric Enzyme Composed of Dimeric Dimers“ |
|
38) |
J. Immunol. 173, 5989-5999, (2004) |
|
H.-Y. Hsu, K.-F. Hua, C.-C. Lin, C.-H. Lin, J. Hsu, C.-H. Wong |
|
“Extract of Reishi Polysaccharides Induces Cytokine Expression via TLR4-Modulated Protein Kinase Signaling pathways” |
|
37) |
Chem. & Biol. 11, 1301-1306, (2004) |
|
C.-F. Chang, C.-W. Ho, C.-Y. Wu, C.-H. Wong, C.-H. Lin |
|
“Discovery of Picomolar Slow Tight-Binding Inhibitors of α-Fucosidase” |
|
36) |
Bioorgaic & Medicinal Chemistry. 12, 5595-5601, (2004) |
|
H.-S. Chen, Y.-F. Tsai, S. Lin, K.-H. Khoo, C.-H. Wong, C.-H. Lin |
|
“Studies on the Immuno-modulating and anti-tumor activities of Ganoderma lucidum (Reishi) Polysaccharides” |
|
35) |
Glycobiology. 14, 147-155, (2004) |
|
M.-C. Cheng, C.-H. Lin, Heng-Ru Lin, Yu-Ping Yu, S.-H. Wu* |
|
“Hydrolysis, Lactonization, and Identification of α2,8-/α-2,9- Alternately Linked Tri-, Tetra, and Polysialic Acids” |
|
34) |
The Proceedings of the International Symposium on Biomolecular Chemistry 2003. Maruzen Co.: Tokyo, p. 96-99 (2003) |
|
Y.-J. Chen, T.-S. Hwang, X.-H. Hwnag, H.-K. Liao, C.-H. Lin |
|
“Sialic Acid Synthase from Escherichia coli - Structural Characterization by Mass Spectrometry” |
|
33) |
Angew. Chem. Int. Ed. 42, 4661-4664, (2003) |
|
C.-Y. Wu, C.-F. Chang, S.-Y. Chen, C.-H. Wong, C.-H. Lin |
|
“Rapid Diversity-Oriented Synthesis in Microtiter Plates for In Situ Screening: Discovery of Potent and Selective α-Fucosidase inhibitors” |
|
32) |
Org. Lett. 5, 1087-1089, (2003) |
|
W.-B. Yang, H.-C. Lin, Y.-F. Gu, C.-Y. Chen, C.-Y. Wu, C.-C., C.-H. Lin |
|
“Stereoselective Glycosylation of exo-Glycals Accelerated by Ferrier-type Rearrangement” |
|
31) |
Tetrahedron Letters 43, 6515-6519, (2002) |
|
C.-F. Chang, W.-B. Yang, C.-C. Chang, C.-H. Lin |
|
“Inter- and Intramolecular alcohol additions of exo-Glycals” |
|
30) |
J. Org. Chem. 67, 3773-3782, (2002) |
|
W.-B. Yang, Y.-Y. Yang, Y.-F. Gu, S.-H. Wang, C.-C. Chang, C.-H. Lin |
|
“Stereochemistry in the Synthesis and Reaction of exo-Glycals” |
|
29) |
Biochem. Biophys. Res. Commun. 295, 167-173, (2002) |
|
T.-S. Hwang, C.-H. Hung, C.-F. Teo, G.-T. Chen, L.-S. Chang, S.-F. Chen, Y.-J. Chen, C.-H. Lin |
|
“Structural Characterization of Escherichia coli Sialic Acid Synthase” |
|
28) |
Bioorgaic & Medicinal Chemistry. 10, 1057-1062, (2002) |
|
Y.-Y. Wang, K.-H. Khoo, S.-T. Chen, C.-C. Lin, C.-H. Wong, C.-H. Lin |
|
“Studies on the Immuno-modulating and Antitumor Activities of Ganoderma lucidum (Reishi) Polysaccharides: Functional and Proteomic Analysis of a Fucose-containing Glycoprotein Fraction Responsible for the Activities” |
|
27) |
Tetrahedron 58, 253-259, (2002) |
|
W.-B. Yang, Sachindra S. Patil, C.-H. Tsai, C.-H. Lin, J.-M. Fang |
|
“The Synthesis of L-Gulose and L-Xylose from D-gluconolactone” |
|
26) |
Tetrahedron Letters 42, 6907-6910, (2001) |
|
W.-B. Yang, T.-I. Wu, C.-C. Chang, S.-H. Wang, C.-F. Teo, C.-H. Lin |
|
“Facile Synthesis of Conjugated exo-Glycals” |
|
25) |
Tetrahedron Letters 42, 4567-4660, (2001) |
|
W.-B. Yang, C.-F. Chang, S.-H. Wang, C.-F. Teo, C.-H. Lin |
|
“Expeditious Synthesis of C-Glycosyl Conjugated Dienes and Aldehydes from Sugar Lactones” |
|
24) |
Adv Exp Med Biol. 491, 215-230, (2001) |
|
C.-H. Lin, C.-C. Lin |
|
“Enzymatic and Chemical Approaches for the Synthesis of Sialyl Glycoconjugates” |
|
23) |
J. Org. Chem. 66, 5248-5251, (2001) |
|
Y.-P. Yu, M.-C. Cheng, H.-R. Lin, Y.-F. Tsai, C.-H. Lin, S.-H. Wu |
|
“Acid-Catalyzed Hydrolysis and Lactonization of α2,8-Linked Oligosialic Acid” |
|
22) |
Angew. Chem. Int. Ed. 39, 772-776 (2000) |
|
M.-C. Cheng, C.-H. Lin, H.-Y. Wang, H.-R. Lin, S.-H. Wu |
|
“Regioselective Lactonization of Tetrasialic Acid” |
|
21) |
J. Org. Chem. 65, 5565-5574, (2000) |
|
M. D. Burkart, M. Izumi, E. Chapman, C.-H. Lin, C.-H. Wong |
|
“Regeneration of PAPS for the Enzymatic Synthesis of Sulfated Oligosaccharides” |
|
20) |
Synlett 2000, 1634-1636, (2000) |
|
Y.-Y. Yang, W.-B. Yang, C.-F. Teo, C.-H. Lin |
|
“Regioselective Deprotection of tert-Butyldimethylsilyl Ethers by Boron Trichloride” |
|
19) |
Tetrahedron Letters 41, 2569-2572, (2000) |
|
W.-B. Yang, C.-H. Tsai, C.-H. Lin |
|
“The Expeditious Preparation and Reactivity of Some Protected Forms of Gluconolactone” |
|
18) |
“Sialobiology and Other Novel Forms of Glycosylation” Edited by Y. Inoue, Y.-C. Lee, F. A. Troy II; Gakushin Publishing Company: Osaka, p. 45-50 (1999) |
|
Lin, C. H.; Cheng, M. C.; Khoo, K. H.; Wu, S. H. |
|
“Regioselective Lactonization of α-2,8-Trisialic Acid” |
|
17) |
Angew. Chem. Int. Ed. 38, 686-689, (1999) |
|
M.-C. Cheng, C.-H. Lin, K.-K. Khoo, S.-H. Wu |
|
“Regioselective Lactonization of α-2,8-Trisialic Acid” |
|
16) |
Chemitstry & Biology 4, 859-866 (1997) |
|
C.-H. Lin, S. Chen, D. S. Kwon, J. K. Coward, C. T. Walsh |
|
“Aldehyde and Phosphinate Analogs of Glutathione and Glutathionyl--spermidine: Potent, Selective Binding Inhibitors of the E. coli Bifunctional Glutathionylspermidine Synthetase/Amidase” |
|
15) |
Biochemistry 36, 14930-14938 (1997) |
|
C.-H. Lin, D. S. Kwon, J. M. Borlinger, Jr., C. T. Walsh |
|
“Evidence for a Glutathionyl-enzyme Intermediate in the Amidase Activity of the Bifunctional Glutathionylspermidine Synthetase/Amidase from Escherichia coli” |
|
14) |
J. Med. Chem. 40, 3842-3850 (1997) |
|
S. Chen, C.-H. Lin, D. S. Kwon, C. T. Walsh, J. K. Cowar |
|
“Design, Synthesis, and Biochemical Evaluation of Phosphonate and Phosphonamidate Analogs of Glutathionylspermidine as Inhibitors of Glutathionylspermidine Synthetase/Amidase from Escherichia coli” |
|
13) |
Proc. Natl. Acad. Sci. USA 94, 10040-10044 (1997) |
|
I.-S. Park, C.-H. Lin, C. T. Walsh |
|
“Bacterial Resistance to Vancomycin: Overproduction, Purification, and Characterizationof VanC2 from Enterococcus casseliflavus as a D-Alanyl-D-Serine Ligase” |
|
12) |
Bioorg. Med. Chem. Lett. 7, 505-510 (1997) |
|
S. Chen, C.-H. Lin, C. T. Walsh, J.K. Coward |
|
“Novel Inhibitors of Trypanothione Biosynthesis: Synthesis and Evaluation of a Phosphinate Analog of Glutathionyl Spermidine (GSP), A Potent, Slow-Binding Inhibitor of GSP Synthetase” |
|
11) |
J. Biol. Chem. 272, 2429-2436 (1997) |
|
D. S. Kwon, C.-H. Lin, S. Chen, J. K. Coward, C. T. Walsh, J. M. Borlinger, Jr. |
|
“Dissection of of Glutathionyl Spermidine Synthetase/Amidase from E. coli into Autonomously Folding and Functional Synthetase and Amidase Domains” |
|
10) |
Tetrahedron Letters 38, 2649-2652 (1997) |
|
C.-C. Lin, C.-H. Lin, C.-H. Wong |
|
“Sialic Acid Aldolase-Catalyzed Condensation of Pyruvate and N-Substituted Mannosamine: A Useful Method for the Synthesis of N-Substituted Sialic Acids” |
|
9) |
Biochemistry 36, 780-785 (1997) |
|
C.-H. Lin, W. M. Brion, I. R. Ollmann, C.-H. Wong |
|
“Why is CMP-Ketodeoxyoctonate Highly Unstable?” |
|
8) |
Biochemistry 35, 10464-10471 (1996) |
|
I.-S. Park, C.-H. Lin, C. T. Walsh |
|
“Gain of D-Alanyl-D-Lactate or D-Lactyl-D-Alanine Synthetase Activities in Three Active Site Mutants of the E. coli D-Alanyl-D-Alanine LigaseB” |
|
7) |
J. Am. Chem. Soc. 117, 8031-8032 (1995) |
|
C.-H. Lin, G.-J. Shen, E. Garcia-Junceda, C.-H. Wong |
|
“Enzymatic Synthesis and Regeneration of 3'-Phosphoadenosine-5'-Phosphosulfate (PAPS) for Regioselective Sulfation of Oligosaccharides” |
|
6) |
Ph.D. Thesis, August (1995) |
|
C.-H. Lin |
|
“Enzymes in Carbohydrate Synthesis” |
|
5) |
Bioorg. Med. Chem. 3, 1625-1630 (1995) |
|
C.-H. Lin, M. Shimazaki, C.-H. Wong, M. Koketsu, L. R. Juneja, M. Kim |
|
“Enzymatic Synthesis of Sialyl Lewis x Dimer from Egg Yolk” |
|
4) |
J. Chem. Soc. Perkin Trans 1, 967-978, (1995) |
|
J.-M. Fang, C.-H. Lin, C. W. Bradshaw, C.-H. Wong |
|
“Enzyme in Organic Synthesis: Oxidoreductions” |
|
3) |
Bioorg. Med. Chem. 3, 313-320, (1995) |
|
T. Sugai, C.-H. Lin, G.-J. Shen, C.-H. Wong |
|
“CMP-KDO Synthetase: Overproduction and Application to the Synthesis of CMP-KDO and Analogs” |
|
2) |
Pure. & Apply. Chem. 65, 803-808 (1993) |
|
C.-H. Wong, Y. Ichikawa, T. Kajimoto, K. K.-C. Liu, G.-J. Shen, C.-H. Lin, Y.-F. Wong, D. P. Dumas, Y.-C. Lin, R. Wang, G. Look |
|
“Practical Synthesis of Carbohydrates Based on Aldolases and Glycosyl Transferases” |
|
1) |
J. Am. Chem. Soc. 114, 10138-10145 (1992) |
|
C.-H. Lin, T. Sugai, R. L. Halcomb, Y. Ichikawa, C.-H. Wong |
|
“Unusual Stereoselectivity in Sialic Acid Aldolase-Catalyzed Aldol Condensations: Synthesis of Both Enantiomers of High Carbon Monosaccharides” |
|
Patents
1) |
C.-H. Wong, C.-H. Lin, US Patent Application Serial No. 07/946,546 (1992) |
|
"Ketoaldonic Acids Having Formed Stereogenic Centers of R-Configuration: Methods and Compositions" |
|
US patent No. 6,353,095, issued in Mar 2002. |
|
2) |
C.-H. Wong, C.-H. Lin, G.-J. Shen. US Patent Application Serial No. 08/408,774, Mar 1995 |
|
"One-pot Enzymatic Sulfation Process Using 3'-Phosphoadenosine-5'-phosphosulfate and Recycled Phosphorylated Adenosine Intermediates " |
|
US patent No. 5,919,673, issued in Jul 1999. |
|
3) |
Y.-Y. Wang, K.-H. Khoo, S.-T. Chen, C.-C. Lin, C.-H. Wong, C.-H. Lin |
|
US Provisional Patent (Sep. 2001) |
|
“Studies on the Immuno-modulating and Antitumor Activities of Ganoderma lucidum (Reishi) Polysaccharides: Functional and Proteomic Analysis of a Fucose-containing Glycoprotein Responsible for the Activities” |
|
4) |
W.-B. Yang, H.-C. Lin, C.-H. Lin |
|
“Stereoselective Glycosylation of exo-Glycals Accelerated by Ferrier-type Rearrangement” Submitted for Patent application |
|
5) |
C.-F. Chang, C.-H Lin |
|
US Provisional Patent |
|
“Rapid Characterization of Sugar-Binding Specificity and Glycan Profiles by In-Solution Proximity Binding with Photosensitizers” |
|
6) |
C.-W. Ho and C.-H. Lin |
|
US Provisional Patent |
|
“Discovery of Potent and Selective Hexosaminidase Inhibitors for Therapeutic Development” |
|
7) |
T.-W. Liu and C.-H. Lin |
|
US Patent (Application No. 12/806,084 filed on August 2, 2010) |
|
“Role of humanα-L-fucosidase 2 in the diagnosis and therapeutic target for Helicobacter pylori-associated gastric diseases” |
|
Others
1) |
中研院周報1001期 |
|
2) |
健康靈芝2005春季號 |
|
|
|
|
Browser & IE Recommendations: 1024*768 / IE 7.0、Firefox 3.0 Add : 128 Sec. 2, Academia Road, Nankang,Taipei 115,Taiwan Tel : 886-2-27855696 Fax : 886-2-27889759 |
Copyright © 2010 IBC. All rights reserved. |
|
|
|